Students will learn the current state-of-the art and future directions in applications of AI and big data. Several real-world applications of AI will be introduced. These include biomedicine, health care, robotics, computer vision, smart homes, and social good. For these areas, we will explore the fundamental challenges, principles, and potential opportunities for future research. We will learn the fundamentals of big data, existing big data platforms and tools, data privacy and data visualization. We will explore several applications of big data in finance, multimedia, health, and social data.