Information Systems vs. Information Technology: A Comprehensive Guide to Choosing the Right Degree for Your Career

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If you’re exploring career paths in tech, you’ve likely heard terms such as information systems (IS) and information technology (IT) used together, or even interchangeably. While these fields are closely related, they represent distinct areas within the tech industry, each with its own academic focus, skill set and career opportunities.

Whether you choose to specialize in IT or IS, earning a graduate degree can be a powerful way to expand your expertise, create opportunities for leadership roles and increase your value in a technology-focused job market.

In this guide, we’ll break down the differences between IS and IT, compare degrees side-by-side and help you determine which option is the right fit for your career.

What Are Information Systems?

Information systems refers to the coordinated set of people, processes, data and technology that organizations use to collect, process, store and distribute information. The goal of IS is to support better decision-making, coordination, control and analysis, ultimately helping businesses gain insights and operate more efficiently. Unlike fields that focus solely on hardware or software, information systems emphasizes the interaction between technology and business strategy.

Educational Pathways

Students interested in an IS career can take several academic routes to get there. Popular avenues include:

Career Opportunities

Graduates with an IS background are uniquely qualified for roles that straddle business and technology. Common career paths include:

  • Business Analyst
  • Data Analyst
  • Information Systems Manager
  • ERP Consultant
  • Solutions Architect
  • Systems Analyst
  • Director of Information Systems
  • Chief Information Officer (CIO)

Job Outlook

The demand for professionals with expertise in information systems continues to be strong. According to projections from the U.S. Bureau of Labor Statistics, employment in IS-related fields is expected to grow much faster than the average for all occupations, with an average of 356,700 openings projected each year through 2033.

What Is Information Technology?

Information technology deals with the use of computers, networks, storage systems and other digital infrastructure to process, store, transmit and secure data. While IS focuses on the integration of technology and business processes, IT is more concerned with the technical foundation that makes those processes possible. Broadly, IT encompasses four core areas:

  1. Hardware: Physical devices, such as servers and computers
  2. Software: The applications, operating systems and tools that run using hardware
  3. Databases: Systems used for storing, retrieving and managing structured information
  4. Networks: The connections that enable systems and users to communicate

Educational Pathways

Students pursuing careers in the IT field have a wide range of academic options:

Career Opportunities

Information technology professionals ensure that the digital backbone of an organization runs smoothly and securely. Common roles include:

  • Network or Systems Administrator
  • Database Administrator
  • Support Specialist
  • Systems Engineer
  • Cybersecurity Analyst
  • IT Manager
  • DevOps Engineer
  • Chief Information Officer (CIO)

Job Outlook

Thanks to the continued demand for cloud services, cybersecurity expertise and data-driven operations across nearly every industry, prospects for IT roles are bright. Since IT and IS are closely linked, growth in the IT field is expected to follow the same trajectory.

Information Systems vs. Information Technology

Although information systems and information technology are closely related, there are key differences that make each a distinct discipline, highlighted in the chart below.

CategoryInformation Systems (IS)Information Technology (IT)
Primary FocusIntegrating people, processes, data and technology to support decision-making and business strategyDesigning, maintaining and securing the technical infrastructure that enables digital operations
Skills NeededBusiness analysis, systems design, data management, project management, organizational strategyNetworking, database administration, programming, cybersecurity, systems engineering, server management
Common CoursesManagement Information Systems, Business Analytics, Database Management, Enterprise Systems, IT Project ManagementComputer Networks, Operating Systems, Software Engineering, Cybersecurity Fundamentals, Cloud Computing
Common Job TitlesBusiness analyst, data analyst, systems analyst, ERP consultant, information systems manager, CIONetwork administrator, systems engineer, database administrator, cybersecurity analyst, IT manager, CIO
Salary Range (Varies by role, employer, location and experience)~$65,000–$160,000+~$60,000–$155,000+
Leadership PotentialStrong pathways into business-oriented leadership roles (e.g., director of IS, CIO, chief data officer)Strong pathways into technology-oriented leadership roles (e.g., IT manager, director of IT, CIO, CTO)

While both fields are essential to modern organizations, the key distinction lies in where the focus is placed. IS emphasizes the intersection of business and technology — helping companies use data and processes to inform strategy and decision-making. IT, on the other hand, concentrates on the technical foundation, the hardware, software, networks and security measures that keep systems running.

In terms of careers, IS professionals often move into roles that blend technology with business leadership, while IT professionals tend to specialize in technical expertise with opportunities to advance into senior infrastructure or cybersecurity leadership positions. Both career paths can lead to high-paying roles with strong job security, but the best fit ultimately depends on whether you’re more interested in solving business challenges through technology (information systems) or building and maintaining the technology itself (information technology).

Which Degree Is Right for You?

Deciding between a master’s in information systems and a master’s in information technology ultimately comes down to how your interests, strengths and career goals align with each field.

Choose an MSIS if you…

  • Enjoy figuring out ways for technology to support business strategy
  • Prefer analyzing how data, processes and systems can drive smarter organizational decisions
  • Aspire to roles in systems analysis, enterprise solutions or technology strategy at the leadership level

Choose an MSIT if you…

  • Enjoy hands-on technical work, such as configuring networks, managing databases or strengthening cybersecurity efforts
  • Want to specialize in areas like cloud infrastructure, system architecture or software development
  • Aspire to lead IT departments or move into senior roles focused on enterprise infrastructure and operations

Bridge the Gap With a Degree From USD

If you’re drawn to aspects of both IS and IT, the Master of Science in Information Technology Leadership from the University of San Diego offers a powerful way to bridge the gap. This program is designed to develop leaders who not only understand the technical foundations of IT but also know how to strategically leverage technology to achieve organizational goals — an ability that’s increasingly essential in today’s digital economy.

With a curriculum that emphasizes leadership development, strategic planning and real-world application, students gain the tools and knowledge to lead IT teams while also shaping high-level technology strategy. The program’s flexible online format makes it possible to balance graduate study with professional and personal responsibilities, while courses focus on core areas such as cybersecurity leadership, DevOps and enterprise applications, data management and reporting.

Whether you see yourself guiding IT infrastructure or steering technology-enabled business transformation, USD’s MS in Information Technology Leadership equips you with the vision and skills to succeed.

Visit our program page today to request more information and see how this degree can help you advance your career.


Frequently Asked Questions

What is the difference between IT and IS?

The main difference lies in focus: information technology (IT) centers on the technical side — hardware, software, networks and security — while information systems (IS) emphasizes how people, processes and technology work together to support business strategy and decision-making.

Do I need a tech background in order to pursue a career in IT or IS?

Not necessarily. While a technical foundation is helpful, many IS programs welcome students with business or management backgrounds who want to learn how technology supports strategy. IT programs typically assume more comfort with technical work but provide training in core areas like networking, programming and databases.

Is an MSIT or MSIS degree better for me?

Neither is “better” overall, as it depends on your career goals. An MSIT is ideal if you enjoy hands-on technical work and want to lead IT infrastructure, cybersecurity or software projects. An MSIS is a better fit if you’re more interested in analyzing systems, managing information and aligning technology with business needs.

What kinds of jobs can I get with an MSIT?

Graduates with an MSIT often pursue roles such as network administrator, systems engineer, database administrator, cybersecurity analyst, IT manager, DevOps engineer or CIO.

What kinds of jobs can I get with an MSIS?

An MSIS prepares students for roles like business analyst, systems analyst, ERP consultant, information systems manager, data analyst, director of information systems or CIO.

How does earning my MSIT or MSIS prepare me for leadership roles?

Both degrees can open doors to leadership positions, but in different ways. An MSIT prepares students to lead technical teams and oversee enterprise infrastructure. An MSIS teaches the skills needed to guide technology strategy, manage systems that support business functions and align IT initiatives with organizational goals.


Are You Asking the Right Questions for Your IT Career? 

Finding the right master’s program in IT Leadership can be the key to your future success. Use our free eBook as a guide to ask the most important questions that will advance your career.

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